His primary areas of study are Computational biology, RNA, Transcription, Cell biology and Data science. In his most recent research, the most cited papers focused on: Subcellular mRNA Localization Regulates Ribosome Biogenesis in Migrating Cells.How Do You Identify m6 A Methylation in Transcriptomes at High Resolution? A Comparison of Recent Datasets.Genetics covers Jernej Ule research in Intron. The RNA splicing study combines topics in areas such as N6-Methyladenosine, Binding site, Intron and Helicase. His ICLIP research includes elements of Published Erratum and MEDLINE. His work carried out in the field of Computational biology brings together such families of science as Chromatin, Genome, RNA-binding protein and Methylation. His RNA study combines topics from a wide range of disciplines, such as Immunoprecipitation and Exon. His scientific interests lie mostly in Cell biology, RNA, Computational biology, ICLIP and Transcription. In recent papers he was focusing on the following fields of study: What were the highlights of his more recent work (between 2019-2021)? His research in Computational biology focuses on subjects like DNA sequencing, which are connected to Reverse transcriptase. The various areas that Jernej Ule examines in his RNA splicing study include Intron and Alternative splicing, Exon. His HITS-CLIP study in the realm of RNA-binding protein connects with subjects such as Context. His Cell biology research is multidisciplinary, incorporating elements of Translation, Chromatin, Gene expression and Transcription. His RNA research focuses on ICLIP in particular. The scientist’s investigation covers issues in RNA, Cell biology, RNA-binding protein, RNA splicing and Computational biology. What are the main themes of his work throughout his whole career to date? iCLIP reveals the function of hnRNP particles in splicing at individual nucleotide resolution (804 citations).CLIP identifies Nova-regulated RNA networks in the brain.HITS-CLIP yields genome-wide insights into brain alternative RNA processing (1054 citations).His study focuses on the intersection of RNA-binding protein and fields such as Binding site with connections in the field of Primer extension, RNA Biochemistry and cDNA library. He has researched ICLIP in several fields, including Minigene and Immunoprecipitation. His RNA splicing research includes themes of Alternative splicing, Exon, Cell biology and Intron. In most of his Genetics studies, his work intersects topics such as Computational biology. His research in RNA intersects with topics in RNA methylation, Molecular biology and Regulation of gene expression. His primary areas of investigation include RNA, Genetics, RNA splicing, ICLIP and RNA-binding protein. doi: 10.1002/wrna.What is he best known for? The fields of study he is best known for:
Iclip genetics software#
We review the different software tools and databases available to analyze the most widely used CLIP methods, HITS-CLIP, PAR-CLIP, and iCLIP. Here, we focus on state-of-the-art molecular biology techniques that employ crosslinking and immunoprecipitation (CLIP) of an RBP to study and map RNP interactions. Accordingly, laboratories interested in RNP biology face the challenge of choosing adequately among the available software tools those that best address the biological problem they are studying. The molecular biology techniques and the computational approaches to understand RBP–RNA (or ribonucleoprotein, RNP) interactions have advanced considerably over the past few years and numerous and diverse software tools have been developed to analyze these data. Investigating the interactions of RNA-binding proteins (RBPs) with RNAs is a complex task for molecular and computational biologists.
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